Identification of a Putative Protein Profile Associated with Tamoxifen Therapy Resistance in Breast Cancer

Tamoxifen resistance is a major cause of death in patients with recurrent breast cancer. Current clinical factors can correctly predict therapy response in only half of the treated patients. Identification of proteins that are associated with tamoxifen resistance is a first step toward better respon...

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Veröffentlicht in:	Molecular & cellular proteomics 2009-06, Vol.8 (6), p.1278-1294
Hauptverfasser:	Umar, Arzu, Kang, Hyuk, Timmermans, Annemieke M., Look, Maxime P., Meijer-van Gelder, Marion E., den Bakker, Michael A., Jaitly, Navdeep, Martens, John W.M., Luider, Theo M., Foekens, John A., Paša-Tolić, Ljiljana
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Chromatography, Liquid Drug Resistance, Neoplasm Female Humans Immunohistochemistry Molecular Sequence Data Neoplasm Proteins - chemistry Neoplasm Proteins - metabolism Peptide Mapping Tamoxifen - therapeutic use Tandem Mass Spectrometry Trypsin - chemistry
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