Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly

Distinct pathways from centrosomes and chromatin are thought to contribute in parallel to microtubule nucleation and stabilization during animal cell mitotic spindle assembly, but their full mechanisms are not known. We investigated the function of three proposed nucleation/stabilization factors, TP...

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Veröffentlicht in:	Molecular biology of the cell 2009-06, Vol.20 (11), p.2766-2773
Hauptverfasser:	Groen, Aaron C, Maresca, Thomas J, Gatlin, Jesse C, Salmon, Edward D, Mitchison, Timothy J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Chromatin - metabolism Female Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Humans Kinesin - metabolism Kinetics Microscopy, Fluorescence - methods Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Microtubules - metabolism Nuclear Proteins - genetics Nuclear Proteins - metabolism Oocytes - cytology Oocytes - metabolism Phosphoproteins - genetics Phosphoproteins - metabolism Spindle Apparatus - metabolism Time Factors Tubulin - genetics Tubulin - metabolism Xenopus laevis Xenopus Proteins - genetics Xenopus Proteins - metabolism
Online-Zugang:	Volltext
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