InterPro: the integrative protein signature database
The InterPro database (http://www.ebi.ac.uk/interpro/) integrates together predictive models or 'signatures' representing protein domains, families and functional sites from multiple, diverse source databases: Gene3D, PANTHER, Pfam, PIRSF, PRINTS, ProDom, PROSITE, SMART, SUPERFAMILY and TI...
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| Veröffentlicht in: | Nucleic acids research 2009-01, Vol.37 (suppl-1), p.D211-D215 |
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| container_title | Nucleic acids research |
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| creator | Hunter, Sarah Apweiler, Rolf Attwood, Teresa K Bairoch, Amos Bateman, Alex Binns, David Bork, Peer Das, Ujjwal Daugherty, Louise Duquenne, Lauranne Finn, Robert D Gough, Julian Haft, Daniel Hulo, Nicolas Kahn, Daniel Kelly, Elizabeth Laugraud, Aurélie Letunic, Ivica Lonsdale, David Lopez, Rodrigo Madera, Martin Maslen, John McAnulla, Craig McDowall, Jennifer Mistry, Jaina Mitchell, Alex Mulder, Nicola Natale, Darren Orengo, Christine Quinn, Antony F Selengut, Jeremy D Sigrist, Christian J.A Thimma, Manjula Thomas, Paul D Valentin, Franck Wilson, Derek Wu, Cathy H Yeats, Corin |
| description | The InterPro database (http://www.ebi.ac.uk/interpro/) integrates together predictive models or 'signatures' representing protein domains, families and functional sites from multiple, diverse source databases: Gene3D, PANTHER, Pfam, PIRSF, PRINTS, ProDom, PROSITE, SMART, SUPERFAMILY and TIGRFAMs. Integration is performed manually and approximately half of the total ~58 000 signatures available in the source databases belong to an InterPro entry. Recently, we have started to also display the remaining un-integrated signatures via our web interface. Other developments include the provision of non-signature data, such as structural data, in new XML files on our FTP site, as well as the inclusion of matchless UniProtKB proteins in the existing match XML files. The web interface has been extended and now links out to the ADAN predicted protein-protein interaction database and the SPICE and Dasty viewers. The latest public release (v18.0) covers 79.8% of UniProtKB (v14.1) and consists of 16 549 entries. InterPro data may be accessed either via the web address above, via web services, by downloading files by anonymous FTP or by using the InterProScan search software (http://www.ebi.ac.uk/Tools/InterProScan/). |
| doi_str_mv | 10.1093/nar/gkn785 |
| format | Article |
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Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nucleic acids research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hunter, Sarah</au><au>Apweiler, Rolf</au><au>Attwood, Teresa K</au><au>Bairoch, Amos</au><au>Bateman, Alex</au><au>Binns, David</au><au>Bork, Peer</au><au>Das, Ujjwal</au><au>Daugherty, Louise</au><au>Duquenne, Lauranne</au><au>Finn, Robert D</au><au>Gough, Julian</au><au>Haft, Daniel</au><au>Hulo, Nicolas</au><au>Kahn, Daniel</au><au>Kelly, Elizabeth</au><au>Laugraud, Aurélie</au><au>Letunic, Ivica</au><au>Lonsdale, David</au><au>Lopez, Rodrigo</au><au>Madera, Martin</au><au>Maslen, John</au><au>McAnulla, Craig</au><au>McDowall, Jennifer</au><au>Mistry, Jaina</au><au>Mitchell, Alex</au><au>Mulder, Nicola</au><au>Natale, Darren</au><au>Orengo, Christine</au><au>Quinn, Antony F</au><au>Selengut, Jeremy D</au><au>Sigrist, Christian J.A</au><au>Thimma, Manjula</au><au>Thomas, Paul D</au><au>Valentin, Franck</au><au>Wilson, Derek</au><au>Wu, Cathy H</au><au>Yeats, Corin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>InterPro: the integrative protein signature database</atitle><jtitle>Nucleic acids research</jtitle><addtitle>Nucleic Acids Res</addtitle><date>2009-01-01</date><risdate>2009</risdate><volume>37</volume><issue>suppl-1</issue><spage>D211</spage><epage>D215</epage><pages>D211-D215</pages><issn>0305-1048</issn><eissn>1362-4962</eissn><coden>NARHAD</coden><abstract>The InterPro database (http://www.ebi.ac.uk/interpro/) integrates together predictive models or 'signatures' representing protein domains, families and functional sites from multiple, diverse source databases: Gene3D, PANTHER, Pfam, PIRSF, PRINTS, ProDom, PROSITE, SMART, SUPERFAMILY and TIGRFAMs. Integration is performed manually and approximately half of the total ~58 000 signatures available in the source databases belong to an InterPro entry. 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| identifier | ISSN: 0305-1048 |
| ispartof | Nucleic acids research, 2009-01, Vol.37 (suppl-1), p.D211-D215 |
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| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2686546 |
| source | Oxford Journals Open Access Collection; MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Databases, Protein Life Sciences Other Proteins - chemistry Proteins - classification Sequence Analysis, Protein Systems Integration |
| title | InterPro: the integrative protein signature database |
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