GABA Regulates Excitatory Synapse Formation in the Neocortex via NMDA Receptor Activation

The development of a balance between excitatory and inhibitory synapses is a critical process in the generation and maturation of functional circuits. Accumulating evidence suggests that neuronal activity plays an important role in achieving such a balance in the developing cortex, but the mechanism...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of neuroscience 2008-05, Vol.28 (21), p.5547-5558
Hauptverfasser:	Wang, Doris D, Kriegstein, Arnold R
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology Animals Animals, Newborn Bumetanide - pharmacology Excitatory Amino Acid Agonists - pharmacology Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology gamma-Aminobutyric Acid - pharmacology Green Fluorescent Proteins - biosynthesis Mice Mice, Transgenic Mutation N-Methylaspartate - pharmacology Neocortex - cytology Neocortex - growth & development Neurons - drug effects Neurons - physiology Patch-Clamp Techniques - methods Receptors, N-Methyl-D-Aspartate - genetics Receptors, N-Methyl-D-Aspartate - physiology Sodium Potassium Chloride Symporter Inhibitors - pharmacology Sodium-Potassium-Chloride Symporters - deficiency Solute Carrier Family 12, Member 2 Synapses - drug effects Synapses - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!