SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function

Caveolae are a major membrane domain common to most cells. One of the defining features of this domain is the protein caveolin. The exact function of caveolin, however, is not clear. One possible function is to attract adapter molecules to caveolae in a manner similar to how clathrin attracts molecu...

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Veröffentlicht in:	The EMBO journal 2009-04, Vol.28 (8), p.1001-1015
Hauptverfasser:	McMahon, Kerrie-Ann, Zajicek, Hubert, Li, Wei-Ping, Peyton, Michael J, Minna, John D, Hernandez, V James, Luby-Phelps, Katherine, Anderson, Richard G W
Format:	Artikel
Sprache:	eng
Schlagworte:	adapter protein Animals Binding sites Carrier Proteins - genetics Carrier Proteins - metabolism caveolae Caveolae - metabolism caveolin Caveolins - genetics Caveolins - metabolism Cell Line Cellular biology Cytoplasmic Vesicles - metabolism Cytoplasmic Vesicles - ultrastructure EMBO20 endocytosis Fibroblasts - cytology Fibroblasts - metabolism Fluorescence Recovery After Photobleaching Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Membranes Mice Mice, Knockout Molecular biology Mutagenesis, Site-Directed Phosphate-Binding Proteins Protein Isoforms - genetics Protein Isoforms - metabolism Protein Kinase C - metabolism Proteins Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Tissue Distribution
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