Maternal Di-(2-ethylhexyl)-phthalate Exposure Influences Essential Fatty Acid Homeostasis in Rat Placenta

Abstract Maintaining essential fatty acid (EFA) homeostasis during pregnancy is critical for fetal development. As the organ that controls the maternal-to-fetal supply of nutrients, the placenta plays a significant role in guiding EFA transfer to the fetus. Many EFA homeostasis proteins are regulate...

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Veröffentlicht in:	Placenta (Eastbourne) 2008-11, Vol.29 (11), p.962-969
Hauptverfasser:	Xu, Y, Agrawal, S, Cook, T.J, Knipp, G.T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acid - pharmacokinetics Biological and medical sciences Carbon Radioisotopes Cyclooxygenase 1 - genetics Cytochrome P-450 CYP4A - genetics DEHP Diethylhexyl Phthalate - toxicity Docosahexaenoic Acids - pharmacokinetics Embryology: invertebrates and vertebrates. Teratology Fatty acid Fatty Acid Transport Proteins - genetics Fatty Acids - metabolism Female Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Homeostasis - drug effects Internal Medicine Metabolism Obstetrics and Gynecology Placenta Placenta - drug effects Placenta - physiology Plasticizers - toxicity PPAR PPAR alpha - genetics PPAR gamma - genetics PPAR-beta - genetics Pregnancy Prenatal Exposure Delayed Effects - metabolism Prenatal Exposure Delayed Effects - physiopathology Prostaglandins - metabolism Rat Rats Rats, Sprague-Dawley Transport Tritium
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