Vasoactive Intestinal Polypeptide Entrains Circadian Rhythms in Astrocytes

Many mammalian cell types show daily rhythms in gene expression driven by a circadian pacemaker. For example, cultured astrocytes display circadian rhythms in Period1 and Period2 expression. It is not known, however, how or which intercellular factors synchronize and sustain rhythmicity in astrocyte...

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Veröffentlicht in:	Journal of biological rhythms 2009-04, Vol.24 (2), p.135-143
Hauptverfasser:	Marpegan, Luciano, Krall, Thomas J, Herzog, Erik D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes Astrocytes - cytology Astrocytes - physiology Biological Clocks - physiology Bioluminescence Brain Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cells, Cultured Circadian rhythm Circadian Rhythm - physiology Circadian rhythms Entrainment Gene expression Gene Knock-In Techniques Glial cells In vitro methods and tests Intestine Mice Neuronal-glial interactions Neuropeptides Nuclear Proteins - genetics Nuclear Proteins - metabolism Period 1 protein Period 2 protein Period Circadian Proteins Polypeptides Transcription Factors - genetics Transcription Factors - metabolism Vasoactive agents Vasoactive intestinal peptide Vasoactive Intestinal Peptide - metabolism
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