Tyrosine Nitration of IκBα:  A Novel Mechanism for NF-κB Activation

The NF-κB family of transcription factors is an important component of stress-activated cytoprotective signal transduction pathways. Previous studies demonstrated that some activation mechanisms require phosphorylation, ubiquitination, and degradation of the inhibitor protein, IκBα. Herein, it is de...

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Veröffentlicht in:Biochemistry (Easton) 2007-10, Vol.46 (42), p.11671-11683
Hauptverfasser: Yakovlev, Vasily A, Barani, Igor J, Rabender, Christopher S, Black, Stephen M, Leach, J. Kevin, Graves, Paul R, Kellogg, Glen E, Mikkelsen, Ross B
Format: Artikel
Sprache:eng
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