Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo

LPA (lysophosphatidic acid) is a lipid mediator that stimulates cell proliferation and growth, and is involved in physiological and pathological processes such as wound healing, platelet activation, angiogenesis and the growth of tumours. Therefore defining the mechanisms of LPA production and degra...

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Veröffentlicht in:	Biochemical journal 2009-05, Vol.419 (3), p.611-618
Hauptverfasser:	Tomsig, Jose L, Snyder, Ashley H, Berdyshev, Evgeny V, Skobeleva, Anastasia, Mataya, Chifundo, Natarajan, Viswanathan, Brindley, David N, Lynch, Kevin R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Extracellular Space - metabolism Gene Expression Regulation, Enzymologic Lysophospholipids - blood Lysophospholipids - metabolism Mice Molecular Sequence Data Organ Specificity Phosphatidate Phosphatase - genetics Phosphatidate Phosphatase - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism
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