Side population cells derived from adult human liver generate hepatocyte-like cells in vitro

We sought to determine whether hepatic side population (SP) cells derived from adult human liver possess the potential of a novel candidate hepatic stem cell. Human cadaveric donor liver was subjected to collagenase perfusion and hepatocytes were separated from nonparenchymal cells by differential c...

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Veröffentlicht in:	Digestive diseases and sciences 2005-10, Vol.50 (10), p.1755-1763
Hauptverfasser:	Hussain, Sunny Zaheed, Strom, Stephen C, Kirby, Martha R, Burns, Sean, Langemeijer, Saskia, Ueda, Takahiro, Hsieh, Matthew, Tisdale, John F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult alpha 1-Antitrypsin - metabolism Aryl Hydrocarbon Hydroxylases - metabolism Cell Culture Techniques Cell Differentiation Cell Separation Cytochrome P-450 CYP2B6 Hepatocytes - physiology Humans Keratins - metabolism Leukocyte Common Antigens - metabolism Liver - cytology Oxidoreductases, N-Demethylating - metabolism Phenotype RNA, Messenger - metabolism Stem Cells - cytology
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