Kinetoplastid genomics: The thin end of the wedge
The completion of the genome sequencing projects for major pathogens Trypanosoma brucei, Trypanosoma cruzi and Leishmania major has enabled numerous studies that would have been difficult or impossible to perform otherwise. New technologies in sequencing and protein analyses promise further rapid ex...
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| Veröffentlicht in: | Infection, genetics and evolution genetics and evolution, 2008-12, Vol.8 (6), p.901-906 |
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| creator | Sturm, Nancy R. Martinez, L.L. Isadora Trejo Thomas, Sean |
| description | The completion of the genome sequencing projects for major pathogens
Trypanosoma brucei,
Trypanosoma cruzi and
Leishmania major has enabled numerous studies that would have been difficult or impossible to perform otherwise. New technologies in sequencing and protein analyses promise further rapid expansion in our capabilities. The keys to successful use of these new tools are recognizing the power and limitations of studies performed thus far, grasping the unrealized potential of new and developing technologies, and creating access to a multidisciplinary set of skills that will facilitate research, particularly in the bioinformatic analysis of the reams of data that will be forthcoming. In this Discussion, we will provide an overview of kinetoplastid genomics studies with emphasis on studies advanced through genomic data, and a preview of what may come in the near future. |
| doi_str_mv | 10.1016/j.meegid.2008.07.001 |
| format | Article |
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Trypanosoma brucei,
Trypanosoma cruzi and
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Trypanosoma brucei,
Trypanosoma cruzi and
Leishmania major has enabled numerous studies that would have been difficult or impossible to perform otherwise. New technologies in sequencing and protein analyses promise further rapid expansion in our capabilities. The keys to successful use of these new tools are recognizing the power and limitations of studies performed thus far, grasping the unrealized potential of new and developing technologies, and creating access to a multidisciplinary set of skills that will facilitate research, particularly in the bioinformatic analysis of the reams of data that will be forthcoming. 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Trypanosoma brucei,
Trypanosoma cruzi and
Leishmania major has enabled numerous studies that would have been difficult or impossible to perform otherwise. New technologies in sequencing and protein analyses promise further rapid expansion in our capabilities. The keys to successful use of these new tools are recognizing the power and limitations of studies performed thus far, grasping the unrealized potential of new and developing technologies, and creating access to a multidisciplinary set of skills that will facilitate research, particularly in the bioinformatic analysis of the reams of data that will be forthcoming. In this Discussion, we will provide an overview of kinetoplastid genomics studies with emphasis on studies advanced through genomic data, and a preview of what may come in the near future.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>18675383</pmid><doi>10.1016/j.meegid.2008.07.001</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Infection, genetics and evolution, 2008-12, Vol.8 (6), p.901-906 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Bioinformatics Computational Biology Genomics - methods Humans Kinetoplastida - genetics Leishmania Leishmania major Leishmania major - genetics Metabolic Networks and Pathways - genetics Proteomics - methods Sequence Analysis, DNA Trypanosoma Trypanosoma brucei Trypanosoma brucei brucei - genetics Trypanosoma cruzi Trypanosoma cruzi - genetics Trypanosome |
| title | Kinetoplastid genomics: The thin end of the wedge |
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