Mechanisms Underlying the Rapid Induction and Sustained Expression of Synaptic Homeostasis

Homeostatic signaling systems are thought to interface with the mechanisms of neural plasticity to achieve stable yet flexible neural circuitry. However, the time course, molecular design, and implementation of homeostatic signaling remain poorly defined. Here we demonstrate that a homeostatic incre...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2006-11, Vol.52 (4), p.663-677
Hauptverfasser:	Frank, C. Andrew, Kennedy, Matthew J., Goold, Carleton P., Marek, Kurt W., Davis, Graeme W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Channels - genetics Calcium Channels - metabolism Calcium Channels, N-Type - genetics Calcium Channels, N-Type - metabolism Compensation Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology Experiments Genotype & phenotype Homeostasis Homeostasis - genetics Insects Membrane Potentials - drug effects Membrane Potentials - genetics MOLNEURO Motor Neurons - drug effects Motor Neurons - metabolism Muscular system Mutation Mutation - genetics Neuromuscular Junction - drug effects Neuromuscular Junction - genetics Neuromuscular Junction - metabolism Receptors, AMPA - antagonists & inhibitors Receptors, AMPA - genetics Receptors, AMPA - metabolism Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Receptors, N-Methyl-D-Aspartate - genetics Receptors, N-Methyl-D-Aspartate - metabolism Rodents SIGNALING Synaptic Membranes - drug effects Synaptic Membranes - genetics Synaptic Membranes - metabolism Synaptic Transmission - drug effects Synaptic Transmission - genetics Synaptic Vesicles - drug effects Synaptic Vesicles - metabolism Time Factors
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