Estradiol-Induced Enhancement of Object Memory Consolidation Involves NMDA Receptors and Protein Kinase A in the Dorsal Hippocampus of Female C57BL/6 Mice

This study examined the role of dorsal hippocampal NMDA receptors and PKA activation in 17β-estradiol (E 2 )-induced enhancement of object memory consolidation. Mice explored two identical objects during training, after which they immediately received intraperitoneal injections of 0.2 mg/kg E 2 , an...

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Veröffentlicht in:	Behavioral neuroscience 2008-06, Vol.122 (3), p.716-721
Hauptverfasser:	Lewis, Michael C, Kerr, Kristin M, Orr, Patrick T, Frick, Karyn M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Animal memory Animals Behavior, Animal - drug effects Behavioral psychophysiology Biological and medical sciences Brain Cyclic AMP - analogs & derivatives Cyclic AMP - pharmacology Cyclic AMP-Dependent Protein Kinases - physiology Drug Interactions Estradiol Estradiol - pharmacology Estrogens Estrogens - pharmacology Excitatory Amino Acid Antagonists - pharmacology Extracellular Signal-Regulated MAP Kinases - metabolism Female Fundamental and applied biological sciences. Psychology Glutamic Acid Hippocampus Hippocampus - drug effects Kinases Memory - drug effects Mice Mice, Inbred C57BL N-Methyl-D-Aspartate Neurosciences Object Recognition Ovariectomy Pattern Recognition, Visual - drug effects Photic Stimulation - methods Protein Kinase Inhibitors - pharmacology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Receptors, N-Methyl-D-Aspartate - physiology Rodents Studies Thionucleotides - pharmacology Valine - analogs & derivatives Valine - pharmacology
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