Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein
Nonobese children age 10.4 +/- 1.1 years diagnosed with dyslipidemia (n = 51) were compared to normal children age 10.8 +/- 1.1 years (n = 38). Affected individuals had increased total cholesterol: 223 +/- 23 vs 152 +/- 17 mg/dl, p < 0.001; and decreased high-density lipoprotein-cholesterol: 41.9...
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| creator | Vázquez, Miguel Arturo Salazar Vázquez, Beatriz Yadira Salazar Intaglietta, M Cabrales, Pedro |
| description | Nonobese children age 10.4 +/- 1.1 years diagnosed with dyslipidemia (n = 51) were compared to normal children age 10.8 +/- 1.1 years (n = 38). Affected individuals had increased total cholesterol: 223 +/- 23 vs 152 +/- 17 mg/dl, p < 0.001; and decreased high-density lipoprotein-cholesterol: 41.9 +/- 4.1 vs 57.6 +/- 5.7 mg/dl, p < 0.001 and triglycerides: 90.8 +/- 40.5 vs 65.7 +/- 25.0 mg/dl, p < 0.002. Fasting glucose was also significantly elevated (p < 0.02). All other parameters, including blood pressure, were not statistically different between groups. The concentration of C-reactive protein was not statistically different between groups. Analysis of medical records showed that this anomaly may be related to this group (as well as the control group) performing regular, daily exercise. This activity was quantified via a self administered questionnaire, and found to be statistically identical in controls and dyslipidemic individuals. Exercise is associated with the release of antiinflammatory cytokines, therefore our results support the contention that it is a significant factor in promoting health conditions from an early stage in life. |
| doi_str_mv | 10.2147/VHRM.S3892 |
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Affected individuals had increased total cholesterol: 223 +/- 23 vs 152 +/- 17 mg/dl, p < 0.001; and decreased high-density lipoprotein-cholesterol: 41.9 +/- 4.1 vs 57.6 +/- 5.7 mg/dl, p < 0.001 and triglycerides: 90.8 +/- 40.5 vs 65.7 +/- 25.0 mg/dl, p < 0.002. Fasting glucose was also significantly elevated (p < 0.02). All other parameters, including blood pressure, were not statistically different between groups. The concentration of C-reactive protein was not statistically different between groups. Analysis of medical records showed that this anomaly may be related to this group (as well as the control group) performing regular, daily exercise. This activity was quantified via a self administered questionnaire, and found to be statistically identical in controls and dyslipidemic individuals. Exercise is associated with the release of antiinflammatory cytokines, therefore our results support the contention that it is a significant factor in promoting health conditions from an early stage in life.</description><identifier>ISSN: 1178-2048</identifier><identifier>ISSN: 1176-6344</identifier><identifier>EISSN: 1178-2048</identifier><identifier>DOI: 10.2147/VHRM.S3892</identifier><identifier>PMID: 19436676</identifier><language>eng</language><publisher>New Zealand: Taylor & Francis Ltd</publisher><subject>Biomarkers - blood ; Blood Glucose - analysis ; Blood Pressure ; Body Mass Index ; C-reactive protein ; C-Reactive Protein - analysis ; Case-Control Studies ; Child ; children ; Cholesterol, HDL - blood ; Diabetes ; dyslipidemia ; Dyslipidemias - blood ; Dyslipidemias - diagnosis ; Dyslipidemias - physiopathology ; Exercise ; Female ; hispanics ; Humans ; inflammation ; Male ; Metabolic disorders ; Metabolic syndrome ; obesity ; Original Research ; Surveys and Questionnaires ; Triglycerides - blood</subject><ispartof>Vascular health and risk management, 2009-01, Vol.5 (1), p.65-9; quiz 70-2</ispartof><rights>2009. 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All rights reserved 2009</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672465/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672465/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,3863,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19436676$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vázquez, Miguel Arturo Salazar</creatorcontrib><creatorcontrib>Vázquez, Beatriz Yadira Salazar</creatorcontrib><creatorcontrib>Intaglietta, M</creatorcontrib><creatorcontrib>Cabrales, Pedro</creatorcontrib><title>Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein</title><title>Vascular health and risk management</title><addtitle>Vasc Health Risk Manag</addtitle><description>Nonobese children age 10.4 +/- 1.1 years diagnosed with dyslipidemia (n = 51) were compared to normal children age 10.8 +/- 1.1 years (n = 38). Affected individuals had increased total cholesterol: 223 +/- 23 vs 152 +/- 17 mg/dl, p < 0.001; and decreased high-density lipoprotein-cholesterol: 41.9 +/- 4.1 vs 57.6 +/- 5.7 mg/dl, p < 0.001 and triglycerides: 90.8 +/- 40.5 vs 65.7 +/- 25.0 mg/dl, p < 0.002. Fasting glucose was also significantly elevated (p < 0.02). All other parameters, including blood pressure, were not statistically different between groups. The concentration of C-reactive protein was not statistically different between groups. Analysis of medical records showed that this anomaly may be related to this group (as well as the control group) performing regular, daily exercise. This activity was quantified via a self administered questionnaire, and found to be statistically identical in controls and dyslipidemic individuals. Exercise is associated with the release of antiinflammatory cytokines, therefore our results support the contention that it is a significant factor in promoting health conditions from an early stage in life.</description><subject>Biomarkers - blood</subject><subject>Blood Glucose - analysis</subject><subject>Blood Pressure</subject><subject>Body Mass Index</subject><subject>C-reactive protein</subject><subject>C-Reactive Protein - analysis</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>children</subject><subject>Cholesterol, HDL - blood</subject><subject>Diabetes</subject><subject>dyslipidemia</subject><subject>Dyslipidemias - blood</subject><subject>Dyslipidemias - diagnosis</subject><subject>Dyslipidemias - physiopathology</subject><subject>Exercise</subject><subject>Female</subject><subject>hispanics</subject><subject>Humans</subject><subject>inflammation</subject><subject>Male</subject><subject>Metabolic disorders</subject><subject>Metabolic syndrome</subject><subject>obesity</subject><subject>Original Research</subject><subject>Surveys and Questionnaires</subject><subject>Triglycerides - blood</subject><issn>1178-2048</issn><issn>1176-6344</issn><issn>1178-2048</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkclqHDEQhoWxiZfkkgcIDYEcjNvWNprWxRCG2A44CWQxuQlJXZqR6ZY6Us_YfnvLmcGbLiWqvvqLqh-h9wQfU8KnJ1cXP78d_2KNpFtoj5BpU1PMm-1n_120n_M1xhPRYPIG7RLJmRBTsYf-fo8hGshwVMEtJOuzD_PKLnzXJghV6_U8xAxtdePHRdXe5c4PvoXe62qhV1CFmHrdVbM6gbajL5khxRF8eIt2nO4yvNvEA_Tn7Mvv2UV9-eP86-zzZW05ZmNtGmtaMIwBdmUDK6UjhgkimGGNxtpRJ8BowYUDx2EiGy2c5IRMjMaENOwAna51h6XpobUQxqQ7NSTf63SnovbqZSX4hZrHlaJiSrmYFIGTtUAbVzAkyPlF81PWxl5RRmTp-LQZmeK_JeRR9T5b6DodIC6zKsKUScwK-PEVeB2XKZRzKFqe5FIIXqjDNWVTzDmBe5xPsHowWD0YrP4bXOAPz9d9QjeOsntHNqRG</recordid><startdate>20090101</startdate><enddate>20090101</enddate><creator>Vázquez, Miguel Arturo Salazar</creator><creator>Vázquez, Beatriz Yadira Salazar</creator><creator>Intaglietta, M</creator><creator>Cabrales, Pedro</creator><general>Taylor & Francis Ltd</general><general>Dove Press</general><general>Dove Medical Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20090101</creationdate><title>Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein</title><author>Vázquez, Miguel Arturo Salazar ; Vázquez, Beatriz Yadira Salazar ; Intaglietta, M ; Cabrales, Pedro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-b8cbdeb33e0f389c99f1b36163b38a0af2f6eba646fef4e598a6f94115ba01183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Biomarkers - blood</topic><topic>Blood Glucose - analysis</topic><topic>Blood Pressure</topic><topic>Body Mass Index</topic><topic>C-reactive protein</topic><topic>C-Reactive Protein - analysis</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>children</topic><topic>Cholesterol, HDL - blood</topic><topic>Diabetes</topic><topic>dyslipidemia</topic><topic>Dyslipidemias - blood</topic><topic>Dyslipidemias - diagnosis</topic><topic>Dyslipidemias - physiopathology</topic><topic>Exercise</topic><topic>Female</topic><topic>hispanics</topic><topic>Humans</topic><topic>inflammation</topic><topic>Male</topic><topic>Metabolic disorders</topic><topic>Metabolic syndrome</topic><topic>obesity</topic><topic>Original Research</topic><topic>Surveys and Questionnaires</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vázquez, Miguel Arturo Salazar</creatorcontrib><creatorcontrib>Vázquez, Beatriz Yadira Salazar</creatorcontrib><creatorcontrib>Intaglietta, M</creatorcontrib><creatorcontrib>Cabrales, Pedro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Vascular health and risk management</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vázquez, Miguel Arturo Salazar</au><au>Vázquez, Beatriz Yadira Salazar</au><au>Intaglietta, M</au><au>Cabrales, Pedro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein</atitle><jtitle>Vascular health and risk management</jtitle><addtitle>Vasc Health Risk Manag</addtitle><date>2009-01-01</date><risdate>2009</risdate><volume>5</volume><issue>1</issue><spage>65</spage><epage>9; quiz 70-2</epage><pages>65-9; quiz 70-2</pages><issn>1178-2048</issn><issn>1176-6344</issn><eissn>1178-2048</eissn><abstract>Nonobese children age 10.4 +/- 1.1 years diagnosed with dyslipidemia (n = 51) were compared to normal children age 10.8 +/- 1.1 years (n = 38). Affected individuals had increased total cholesterol: 223 +/- 23 vs 152 +/- 17 mg/dl, p < 0.001; and decreased high-density lipoprotein-cholesterol: 41.9 +/- 4.1 vs 57.6 +/- 5.7 mg/dl, p < 0.001 and triglycerides: 90.8 +/- 40.5 vs 65.7 +/- 25.0 mg/dl, p < 0.002. Fasting glucose was also significantly elevated (p < 0.02). All other parameters, including blood pressure, were not statistically different between groups. The concentration of C-reactive protein was not statistically different between groups. Analysis of medical records showed that this anomaly may be related to this group (as well as the control group) performing regular, daily exercise. This activity was quantified via a self administered questionnaire, and found to be statistically identical in controls and dyslipidemic individuals. Exercise is associated with the release of antiinflammatory cytokines, therefore our results support the contention that it is a significant factor in promoting health conditions from an early stage in life.</abstract><cop>New Zealand</cop><pub>Taylor & Francis Ltd</pub><pmid>19436676</pmid><doi>10.2147/VHRM.S3892</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Dove Press Free; PubMed Central Open Access; Access via Taylor & Francis (Open Access Collection); EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Biomarkers - blood Blood Glucose - analysis Blood Pressure Body Mass Index C-reactive protein C-Reactive Protein - analysis Case-Control Studies Child children Cholesterol, HDL - blood Diabetes dyslipidemia Dyslipidemias - blood Dyslipidemias - diagnosis Dyslipidemias - physiopathology Exercise Female hispanics Humans inflammation Male Metabolic disorders Metabolic syndrome obesity Original Research Surveys and Questionnaires Triglycerides - blood |
| title | Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein |
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