DNA sequence and structural properties as predictors of human and mouse promoters

Promoters play a central role in gene regulation, yet our power to discriminate them from non-promoter sequences in higher eukaryotes is mainly restricted to those associated with CpG islands. Here, we examined in silico the promoters of 30,954 human and 18,083 mouse transcripts in the DBTSS databas...

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Veröffentlicht in:	Gene 2008-02, Vol.410 (1), p.165-176
Hauptverfasser:	Akan, Pelin, Deloukas, Panos
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATG desert CpG island DNA - chemistry DNA - genetics DNA bendability Genome-wide computational analysis Human Humans Mice Mouse Nucleic Acid Conformation Nucleosome positioning preference Promoter Promoter Regions, Genetic Propeller twist Sequence Analysis, DNA TATA-box
Online-Zugang:	Volltext
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