Interleukin-1β contributes via nitric oxide to the upregulation and functional activity of the zinc transporter Zip14 (Slc39a14) in murine hepatocytes

Zinc metabolism during chronic disease is dysregulated by inflammatory cytokines. Experiments with IL-6 knockout mice show that LPS regulates expression of the zinc transporter, Zip14, by a mechanism that is partially independent of IL-6. The LPS-induced model of sepsis may occur by a mechanism sign...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2009-04, Vol.296 (4), p.G860-G867
Hauptverfasser:	Lichten, Louis A., Liuzzi, Juan P., Cousins, Robert J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Inflammation/Immunity/Mediators
Online-Zugang:	Volltext
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