Isolation, Structure Elucidation, and Synthesis of Eudistomides A and B, Lipopeptides from a Fijian Ascidian Eudistoma sp

Eudistomides A (1) and B (2), two new cyclic peptides, were isolated from a Fijian ascidian Eudistoma sp. These five-residue cystine-linked cyclic peptides are flanked by a C-terminal methyl ester and a 12-oxo- or 12-hydroxy-tetradecanoyl moiety. The complete structures of the eudistomides were dete...

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Veröffentlicht in:	Journal of organic chemistry 2009-02, Vol.74 (3), p.1156-1162
Hauptverfasser:	Whitson, Emily L, Ratnayake, Anokha S, Bugni, Tim S, Harper, Mary Kay, Ireland, Chris M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemistry Chromatography, High Pressure Liquid Exact sciences and technology Lipopeptides - chemistry Lipopeptides - isolation & purification Nuclear Magnetic Resonance, Biomolecular Organic chemistry Peptides Peptides, Cyclic - chemistry Peptides, Cyclic - isolation & purification Preparations and properties Sequence Analysis, Protein Tandem Mass Spectrometry Urochordata - chemistry
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