Inhibition of androstenediol-dependent LNCaP tumour growth by 17α-ethynyl-5α-androstane-3α, 17β-diol (HE3235)

Androst-5-ene-3 β , 17 β -diol (AED) is an adrenal hormone that has been reported to sustain prostate cancer growth after androgen deprivation therapy (ADT). LNCaP cells express a mutated androgen receptor that confers the ability to respond not only to androgen but also to oestrogen and adrenal hor...

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Veröffentlicht in:	British journal of cancer 2009-04, Vol.100 (7), p.1068-1072
Hauptverfasser:	Trauger, R, Corey, E, Bell, D, White, S, Garsd, A, Stickney, D, Reading, C, Frincke, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Drug Resistance Epidemiology Medical sciences Molecular Medicine Nephrology. Urinary tract diseases Oncology Translational Therapeutics Tumors Tumors of the urinary system Urinary tract. Prostate gland
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