What We Know: Findings That Every Theory of Schizophrenia Should Explain
The article summarizes the process used to distill schizophrenia science into 22 facts. These facts consist of 6 basic facts, 3 etiological facts, 6 pharmacological and treatment facts, 5 pathology facts, and 2 behavioral facts that were critically reviewed by the scholarly community through a speci...
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Veröffentlicht in: | Schizophrenia bulletin 2009-05, Vol.35 (3), p.493-508 |
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description | The article summarizes the process used to distill schizophrenia science into 22 facts. These facts consist of 6 basic facts, 3 etiological facts, 6 pharmacological and treatment facts, 5 pathology facts, and 2 behavioral facts that were critically reviewed by the scholarly community through a special initiative in cooperation with the Schizophrenia Research Forum. A subset of 10 of these facts was selected to form a common set of findings to be explained from the different theoretical perspectives included in this special section of Schizophrenia Bulletin. The rationale for this exercise is to distinguish more precisely the areas of agreement and disagreement between theories of schizophrenia and to highlight where more thought and data can make the greatest impact for understanding this disease. |
doi_str_mv | 10.1093/schbul/sbp017 |
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The rationale for this exercise is to distinguish more precisely the areas of agreement and disagreement between theories of schizophrenia and to highlight where more thought and data can make the greatest impact for understanding this disease.</description><identifier>ISSN: 0586-7614</identifier><identifier>EISSN: 1745-1701</identifier><identifier>DOI: 10.1093/schbul/sbp017</identifier><identifier>PMID: 19329559</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Antipsychotic Agents - therapeutic use ; Brain - drug effects ; Brain - pathology ; Chromosome Mapping ; Female ; Genetic Predisposition to Disease - genetics ; Humans ; Male ; Odds Ratio ; Receptors, Dopamine D2 - drug effects ; Receptors, Dopamine D2 - genetics ; Risk Factors ; Schizophrenia - diagnosis ; Schizophrenia - drug therapy ; Schizophrenia - etiology ; Schizophrenia - genetics ; Schizophrenic Psychology ; Sex Ratio ; Theme: Theories of Schizophrenia: Explanatory Power and Inferential Strength Guest Editors</subject><ispartof>Schizophrenia bulletin, 2009-05, Vol.35 (3), p.493-508</ispartof><rights>The Author 2009. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org. 2009</rights><rights>The Author 2009. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c445t-78dd8fe5b770fcfed687bf258a9a4a4b0268b5de8ec2f817c1eb2128ade0b6643</citedby><cites>FETCH-LOGICAL-c445t-78dd8fe5b770fcfed687bf258a9a4a4b0268b5de8ec2f817c1eb2128ade0b6643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669587/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669587/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,309,310,314,723,776,780,785,786,881,1578,23909,23910,25118,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19329559$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MacDonald, Angus W.</creatorcontrib><creatorcontrib>Schulz, S. Charles</creatorcontrib><title>What We Know: Findings That Every Theory of Schizophrenia Should Explain</title><title>Schizophrenia bulletin</title><addtitle>Schizophr Bull</addtitle><description>The article summarizes the process used to distill schizophrenia science into 22 facts. These facts consist of 6 basic facts, 3 etiological facts, 6 pharmacological and treatment facts, 5 pathology facts, and 2 behavioral facts that were critically reviewed by the scholarly community through a special initiative in cooperation with the Schizophrenia Research Forum. A subset of 10 of these facts was selected to form a common set of findings to be explained from the different theoretical perspectives included in this special section of Schizophrenia Bulletin. The rationale for this exercise is to distinguish more precisely the areas of agreement and disagreement between theories of schizophrenia and to highlight where more thought and data can make the greatest impact for understanding this disease.</description><subject>Antipsychotic Agents - therapeutic use</subject><subject>Brain - drug effects</subject><subject>Brain - pathology</subject><subject>Chromosome Mapping</subject><subject>Female</subject><subject>Genetic Predisposition to Disease - genetics</subject><subject>Humans</subject><subject>Male</subject><subject>Odds Ratio</subject><subject>Receptors, Dopamine D2 - drug effects</subject><subject>Receptors, Dopamine D2 - genetics</subject><subject>Risk Factors</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - drug therapy</subject><subject>Schizophrenia - etiology</subject><subject>Schizophrenia - genetics</subject><subject>Schizophrenic Psychology</subject><subject>Sex Ratio</subject><subject>Theme: Theories of Schizophrenia: Explanatory Power and Inferential Strength Guest Editors</subject><issn>0586-7614</issn><issn>1745-1701</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1P3DAQxS3UCra0R65V1EPVS4rt-Cs9VKrQ8iGQOEDF0bKdCTHK2qm9oaV_PVllVSgXTm8089PTGz2EDgj-SnBdHWbX2bE_zHbARO6gBZGMl0Ri8gYtMFeilIKwPfQu5zuMCasF3UV7pK5ozXm9QKc3nVkXN1Cch_j7W3HsQ-PDbS6uN-vlPaSHaYQ4SWyLK9f5v3HoEgRviqsujn1TLP8MvfHhPXrbmj7Dh63uo5_Hy-uj0_Li8uTs6MdF6Rjj61KqplEtcCslbl0LjVDStpQrUxtmmMVUKMsbUOBoq4h0BCwlVJkGsBWCVfvo--w7jHYFjYOwTqbXQ_Irkx50NF7_fwm-07fxXlMhaq7kZPB5a5DirxHyWq98dtD3JkAcsxaSVLLGYgI_vQDv4pjC9JymtOJMYLaJU86QSzHnBO2_JATrTUF6LkjPBU38x-fxn-htIxPwZQbiOLzi9QjS_Z0V</recordid><startdate>20090501</startdate><enddate>20090501</enddate><creator>MacDonald, Angus W.</creator><creator>Schulz, S. 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subjects | Antipsychotic Agents - therapeutic use Brain - drug effects Brain - pathology Chromosome Mapping Female Genetic Predisposition to Disease - genetics Humans Male Odds Ratio Receptors, Dopamine D2 - drug effects Receptors, Dopamine D2 - genetics Risk Factors Schizophrenia - diagnosis Schizophrenia - drug therapy Schizophrenia - etiology Schizophrenia - genetics Schizophrenic Psychology Sex Ratio Theme: Theories of Schizophrenia: Explanatory Power and Inferential Strength Guest Editors |
title | What We Know: Findings That Every Theory of Schizophrenia Should Explain |
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