Sociodemographic and clinical factors associated with depression in epilepsy
Abstract The impact of mood disorders on patients with epilepsy is an important and growing area of research. If clinicians are adept at recognizing which patients with epilepsy are at risk for mood disorders, treatment can be facilitated and morbidity avoided. We completed a case–control study (80...
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Veröffentlicht in: | Epilepsy & behavior 2009-04, Vol.14 (4), p.655-660 |
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creator | Thompson, Alexander W Miller, John W Katon, Wayne Chaytor, Naomi Ciechanowski, Paul |
description | Abstract The impact of mood disorders on patients with epilepsy is an important and growing area of research. If clinicians are adept at recognizing which patients with epilepsy are at risk for mood disorders, treatment can be facilitated and morbidity avoided. We completed a case–control study (80 depressed subjects, 141 nondepressed subjects) to determine the sociodemographic and clinical factors associated with self-reported depression in people with epilepsy. The Patient Health Questionnaire-9 was used to determine clinically significant depression. In multivariate analyses, depressed subjects with epilepsy were significantly less likely than nondepressed subjects to be married or employed and more likely to report comorbid medical problems and active seizures in the past 6 months. Adjusted for all other variables, subjects with epilepsy reporting lamotrigine use were significantly less likely to be depressed (OR = 0.4, 95% CI: 0.2–0.8) compared with those not reporting lamotrigine use. |
doi_str_mv | 10.1016/j.yebeh.2009.02.014 |
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If clinicians are adept at recognizing which patients with epilepsy are at risk for mood disorders, treatment can be facilitated and morbidity avoided. We completed a case–control study (80 depressed subjects, 141 nondepressed subjects) to determine the sociodemographic and clinical factors associated with self-reported depression in people with epilepsy. The Patient Health Questionnaire-9 was used to determine clinically significant depression. In multivariate analyses, depressed subjects with epilepsy were significantly less likely than nondepressed subjects to be married or employed and more likely to report comorbid medical problems and active seizures in the past 6 months. 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subjects | Adult Anticonvulsants - therapeutic use Antidepressive Agents - therapeutic use Case-Control Studies Case–control Comorbidity Demography Depression Depression - epidemiology Depression - therapy Epidemiology Epilepsy Epilepsy - epidemiology Epilepsy - therapy Female Humans Logistic Models Male Middle Aged Neurology Psychiatric Status Rating Scales Seizures Self Concept Surveys and Questionnaires |
title | Sociodemographic and clinical factors associated with depression in epilepsy |
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