Sociodemographic and clinical factors associated with depression in epilepsy

Abstract The impact of mood disorders on patients with epilepsy is an important and growing area of research. If clinicians are adept at recognizing which patients with epilepsy are at risk for mood disorders, treatment can be facilitated and morbidity avoided. We completed a case–control study (80...

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Veröffentlicht in:Epilepsy & behavior 2009-04, Vol.14 (4), p.655-660
Hauptverfasser: Thompson, Alexander W, Miller, John W, Katon, Wayne, Chaytor, Naomi, Ciechanowski, Paul
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container_end_page 660
container_issue 4
container_start_page 655
container_title Epilepsy & behavior
container_volume 14
creator Thompson, Alexander W
Miller, John W
Katon, Wayne
Chaytor, Naomi
Ciechanowski, Paul
description Abstract The impact of mood disorders on patients with epilepsy is an important and growing area of research. If clinicians are adept at recognizing which patients with epilepsy are at risk for mood disorders, treatment can be facilitated and morbidity avoided. We completed a case–control study (80 depressed subjects, 141 nondepressed subjects) to determine the sociodemographic and clinical factors associated with self-reported depression in people with epilepsy. The Patient Health Questionnaire-9 was used to determine clinically significant depression. In multivariate analyses, depressed subjects with epilepsy were significantly less likely than nondepressed subjects to be married or employed and more likely to report comorbid medical problems and active seizures in the past 6 months. Adjusted for all other variables, subjects with epilepsy reporting lamotrigine use were significantly less likely to be depressed (OR = 0.4, 95% CI: 0.2–0.8) compared with those not reporting lamotrigine use.
doi_str_mv 10.1016/j.yebeh.2009.02.014
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Adult
Anticonvulsants - therapeutic use
Antidepressive Agents - therapeutic use
Case-Control Studies
Case–control
Comorbidity
Demography
Depression
Depression - epidemiology
Depression - therapy
Epidemiology
Epilepsy
Epilepsy - epidemiology
Epilepsy - therapy
Female
Humans
Logistic Models
Male
Middle Aged
Neurology
Psychiatric Status Rating Scales
Seizures
Self Concept
Surveys and Questionnaires
title Sociodemographic and clinical factors associated with depression in epilepsy
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