Effects of ginseng saponin on acute cocaine-induced alterations in evoked dopamine release and uptake in rat brain nucleus accumbens

Abstract In traditional medicine, Panax ginseng has been used to treat various behavioral effects of psychostimulants (e.g., cocaine) and other drugs of abuse and to ameliorate withdrawal symptoms. The neurochemical bases for this efficacy, however, remain to be elucidated. We previously used the re...

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Veröffentlicht in:	Brain research 2009-01, Vol.1248, p.184-190
Hauptverfasser:	Nah, Seong-Yeol, Bhatia, Kamal S, Lyles, Johnnie, Ellinwood, Everett H, Lee, Tong H
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Area Under Curve Biological and medical sciences Cocaine Cocaine - pharmacology Cocaine - toxicity Dopamine Dopamine - metabolism Dopamine Uptake Inhibitors - pharmacology Dose-Response Relationship, Drug Electrophysiological Phenomena Fast scan cyclic voltammetry Ginsenosides - pharmacology In Vitro Techniques Male Medical sciences Models, Animal Neurology Neuropharmacology Nucleus accumbens Nucleus Accumbens - physiology Panax ginseng Panax ginseng Ginsenoside Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats Rats, Sprague-Dawley Substance Withdrawal Syndrome - prevention & control
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