Nitric oxide synthase gene polymorphisms and prostate cancer risk

Nitric oxide (NO) induces cytotoxicity and angiogenesis, and may play a role in prostate carcinogenesis, potentially modulated by environmental exposures. We evaluated the association of prostate cancer with genetic polymorphisms in two genes related to intracellular NO: NOS2A [inducible nitric oxid...

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Veröffentlicht in:	Carcinogenesis (New York) 2009-04, Vol.30 (4), p.621-625
Hauptverfasser:	Lee, Kyoung-Mu, Kang, Daehee, Park, Sue Kyung, Berndt, Sonja I., Reding, Douglas, Chatterjee, Nilanjan, Chanock, Stephen, Huang, Wen-Yi, Hayes, Richard B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antioxidants - administration & dosage beta Carotene - administration & dosage Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carotenoids - administration & dosage Case-Control Studies Genotype Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Medical sciences Middle Aged Molecular Epidemiology Nephrology. Urinary tract diseases Nitric Oxide Synthase Type II - genetics Nitric Oxide Synthase Type III - genetics Polymorphism, Genetic - genetics Prostatic Neoplasms - blood Prostatic Neoplasms - genetics Prostatic Neoplasms - prevention & control Risk Factors Tumors Tumors of the urinary system Urinary tract. Prostate gland Vitamin E - administration & dosage
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