Tumor necrosis factor-α downregulates intestinal NHE8 expression by reducing basal promoter activity

NHE8 transporter is a member of the sodium/hydrogen exchanger (NHE) family. This transporter protein is expressed at the apical membrane of epithelial cells of kidney and intestine and contributes to vectorial Na + transport in both tissues. Although NaCl absorption has been shown to be reduced in d...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2009-03, Vol.296 (3), p.C489-C497
Hauptverfasser:	Xu, Hua, Chen, Huacong, Dong, Jiali, Li, Jing, Chen, Rongji, Uno, Jennifer K., Ghishan, Fayez K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Membrane Transporters, Ion Channels, and Pumps
Online-Zugang:	Volltext
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