A preliminary assessment of the effects of ATI-2042 in subjects with paroxysmal atrial fibrillation using implanted pacemaker methodology

Aims ATI-2042 (budiodarone) is a chemical analogue of amiodarone with a half life of 7 h. It is electrophysiologically similar to amiodarone, but may not have metabolic and interaction side effects. The sophisticated electrocardiograph logs of advanced DDDRP pacemakers were used to monitor the effic...

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Veröffentlicht in:	Europace (London, England) England), 2009-04, Vol.11 (4), p.458-464
Hauptverfasser:	Arya, Anita, Silberbauer, John, Teichman, Sam L., Milner, Peter, Sulke, Neil, Camm, A. John
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Amiodarone - analogs & derivatives Anti-Arrhythmia Agents - adverse effects Anti-Arrhythmia Agents - pharmacokinetics Anti-Arrhythmia Agents - therapeutic use Atrial Fibrillation - drug therapy Atrial Fibrillation - physiopathology Benzofurans - adverse effects Benzofurans - pharmacokinetics Benzofurans - therapeutic use Clinical Research Combined Modality Therapy Dose-Response Relationship, Drug Electrocardiography Female Humans Middle Aged Pacemaker, Artificial Prospective Studies Treatment Outcome
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