Electrostatics in the Ribosomal Tunnel Modulate Chain Elongation Rates

Electrostatic potentials along the ribosomal exit tunnel are nonuniform and negative. The significance of electrostatics in the tunnel remains relatively uninvestigated, yet they are likely to play a role in translation and secondary folding of nascent peptides. To probe the role of nascent peptide...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of molecular biology 2008-12, Vol.384 (1), p.73-86
Hauptverfasser:	Lu, Jianli, Deutsch, Carol
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acid Substitution electrostatics Molecular Sequence Data nascent peptide Peptide Chain Elongation, Translational peptide elongation Peptides - chemistry Peptides - genetics Peptides - metabolism Potassium Channels, Voltage-Gated - chemistry Potassium Channels, Voltage-Gated - genetics Potassium Channels, Voltage-Gated - metabolism Ribosomes - chemistry Ribosomes - metabolism RNA, Messenger S4 transmembrane segment Static Electricity Thermodynamics Time Factors translation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!