MACPF/CDC family of pore-forming toxins

Pore-forming toxins (PFTs) are commonly associated with bacterial pathogenesis. In eukaryotes, however, PFTs operate in the immune system or are deployed for attacking prey (e.g. venoms). This review focuses upon two families of globular protein PFTs: the cholesterol-dependent cytolysins (CDCs) and...

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Veröffentlicht in:	Cellular microbiology 2008-09, Vol.10 (9), p.1765-1774
Hauptverfasser:	Rosado, Carlos J, Kondos, Stephanie, Bull, Tara E, Kuiper, Michael J, Law, Ruby H.P, Buckle, Ashley M, Voskoboinik, Ilia, Bird, Phillip I, Trapani, Joseph A, Whisstock, James C, Dunstone, Michelle A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Toxins - chemistry Bacterial Toxins - immunology Cell Membrane - chemistry Cell Membrane - immunology Complement Membrane Attack Complex - chemistry Complement Membrane Attack Complex - immunology Crystallography, X-Ray Gram-Positive Bacteria - immunology Gram-Positive Bacteria - metabolism Gram-Positive Bacteria - pathogenicity Humans Organelles - chemistry Organelles - immunology Perforin - chemistry Perforin - immunology Protein Structure, Secondary Thematic Reviews: Pathogenic Mechanisms and Defense
Online-Zugang:	Volltext
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