A role for plastids in plant protein isoprenylation
Protein isoprenylation refers to the attachment of a C15 farnesyl or C20 geranylgeranyl moiety to a carboxyl terminal cysteine residue. Because protein isoprenyltransferases are cytosolic enzymes, it has long been assumed that the isoprenyl diphosphates used for protein isoprenylation are synthesiz...
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| Veröffentlicht in: | Plant signaling & behavior 2009-03, Vol.4 (3), p.217-218 |
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| container_title | Plant signaling & behavior |
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| creator | Crowell, Dring N. Hemmerlin, Andréa Gerber, Esther Hartmann, Michael Heintz, Dimitri Rohmer, Michel Bach, Thomas J. |
| description | Protein isoprenylation refers to the attachment of a C15 farnesyl or C20 geranylgeranyl moiety to a carboxyl terminal cysteine residue. Because protein isoprenyltransferases are cytosolic enzymes, it has long been assumed that the isoprenyl diphosphates used for protein isoprenylation are synthesized in the cytosol. However, in the present work, we established that the plastidial 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway is predominantly responsible for providing the geranylgeranyl diphosphate for protein geranylgeranylation in tobacco BY-2 cells. |
| doi_str_mv | 10.4161/psb.4.3.7842 |
| format | Article |
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| ispartof | Plant signaling & behavior, 2009-03, Vol.4 (3), p.217-218 |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Addendum Binding Biology Bioscience Calcium Cancer Cell Cycle cysteine cytosol Landes moieties Organogenesis plant proteins plastids Proteins tobacco transferases |
| title | A role for plastids in plant protein isoprenylation |
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