Electron microscopy localization and characterization of functionalized composite organic-inorganic SERS nanoparticles on leukemia cells

We demonstrate the use of electron microscopy as a powerful characterization tool to identify and locate antibody-conjugated composite organic-inorganic nanoparticle (COINs) surface enhanced Raman scattering (SERS) nanoparticles on cells. U937 leukemia cells labeled with antibody CD54-conjugated COI...

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Veröffentlicht in:	Ultramicroscopy 2008-12, Vol.109 (1), p.111-121
Hauptverfasser:	Koh, Ai Leen, Shachaf, Catherine M., Elchuri, Sailaja, Nolan, Garry P., Sinclair, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Immunoconjugates - chemistry Immunoconjugates - ultrastructure Intercellular Adhesion Molecule-1 - chemistry Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure Microscopy, Electron, Scanning - methods Microscopy, Electron, Transmission - methods Scanning Auger electron spectroscopy Scanning electron microscopy SERS nanoparticles on cells Silver - chemistry Spectrum Analysis, Raman - methods Transmission electron microscopy U937 Cells - ultrastructure
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