Pre-clinical and clinical development of a multi-envelope, DNA-Virus-Protein (D-V-P) HIV-1 vaccine

The human immune system has evolved to recognize antigenic diversity, a strength that has been harnessed by vaccine developers to combat numerous pathogens (e.g. pneumococcus, influenza virus, rotavirus). In each case, vaccine cocktails were formulated to include antigenic variants of the target. To...

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Veröffentlicht in:International reviews of immunology 2009-01, Vol.28 (1), p.49-68
Hauptverfasser: Sealy, Robert, Slobod, Karen, Flynn, Patricia, Branum, Kristen, Surman, Sherri, Jones, Bart, Freiden, Pamela, Lockey, Timothy, Howlett, Nanna, Hurwitz, Julia L.
Format: Artikel
Sprache:eng
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