Frailty: An Emerging Research and Clinical Paradigm—Issues and Controversies

Clinicians and researchers have shown increasing interest in frailty. Yet, there is still considerable uncertainty regarding the concept and its definition. In this article, we present perspectives on key issues and controversies discussed by scientists from 13 different countries, representing a di...

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Veröffentlicht in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2007-07, Vol.62 (7), p.731-737
Hauptverfasser: Bergman, Howard, Ferrucci, Luigi, Guralnik, Jack, Hogan, David B., Hummel, Silvia, Karunananthan, Sathya, Wolfson, Christina
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container_issue 7
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container_title The journals of gerontology. Series A, Biological sciences and medical sciences
container_volume 62
creator Bergman, Howard
Ferrucci, Luigi
Guralnik, Jack
Hogan, David B.
Hummel, Silvia
Karunananthan, Sathya
Wolfson, Christina
description Clinicians and researchers have shown increasing interest in frailty. Yet, there is still considerable uncertainty regarding the concept and its definition. In this article, we present perspectives on key issues and controversies discussed by scientists from 13 different countries, representing a diverse range of disciplines, at the 2006 Second International Working Meeting on Frailty and Aging. The following fundamental questions are discussed: What is the distinction, if any, between frailty and aging? What is its relationship with chronic disease? Is frailty a syndrome or a series of age-related impairments that predict adverse outcomes? What are the critical domains in its operational definition? Is frailty a useful concept? The implications of different models and approaches are examined. Although consensus has yet to be attained, work accomplished to date has opened exciting new horizons. The article concludes with suggested directions for future research.
doi_str_mv 10.1093/gerona/62.7.731
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source MEDLINE; Oxford Academic Journals (OUP)
subjects Aged
Aged, 80 and over
Aging
Aging - physiology
Frail Elderly
Humans
Medical research
Older people
Studies
title Frailty: An Emerging Research and Clinical Paradigm—Issues and Controversies
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