Protein–protein interactions involving congenital cataract T5P γC-crystallin mutant: A confocal fluorescence microscopy study

The human lens crystallin gene CRYGC T5P is associated with Coppock-like cataract and has a phenotype of a dust-like opacity of the fetal lens nucleus and deep cortical region. Previous in vitro mutation studies indicate that the protein has changed conformation, solubility, and stability, which may...

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Veröffentlicht in:Experimental eye research 2008-12, Vol.87 (6), p.515-520
Hauptverfasser: Liu, Bing-Fen, Song, Shuhua, Hanson, Mark, Liang, Jack J.-N.
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Sprache:eng
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