Inhibitory Effects of Coptidis rhizoma and Berberine on Cocaine-induced Sensitization

Substantial evidence suggests that the behavioral and reinforcing effects of cocaine can be mediated by the central dopaminergic systems. Repeated injections of cocaine produce an increase in locomotor activity and the expression of tyrosine hydroxylase (TH) in the main dopaminergic areas. Protoberb...

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Veröffentlicht in:Evidence-based complementary and alternative medicine 2009-03, Vol.6 (1), p.85-90
Hauptverfasser: Lee, Bombi, Yang, Chae Ha, Hahm, Dae-Hyun, Choe, Eun Sang, Lee, Hye-Jung, Pyun, Kwang-Ho, Shim, Insop
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Sprache:eng
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