Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control

Centrioles are intriguing cylindrical organelles composed of triplet microtubules. Proteomic data suggest that a large number of proteins besides tubulin are necessary for the formation and maintenance of a centriole's complex structure. Expansion of the preexisting centriole proteome from the...

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Veröffentlicht in:	Molecular biology of the cell 2009-02, Vol.20 (4), p.1150-1166
Hauptverfasser:	Keller, Lani C, Geimer, Stefan, Romijn, Edwin, Yates, 3rd, John, Zamora, Ivan, Marshall, Wallace F
Format:	Artikel
Sprache:	eng
Schlagworte:	Algal Proteins - chemistry Algal Proteins - metabolism Amino Acid Sequence Animals Axoneme - metabolism Axoneme - ultrastructure Centrioles - metabolism Centrioles - ultrastructure Chlamydomonas reinhardtii - cytology Chlamydomonas reinhardtii - metabolism Chlamydomonas reinhardtii - ultrastructure Conserved Sequence Disease - genetics Fluorescent Antibody Technique Humans Microtubules - metabolism Microtubules - ultrastructure Molecular Sequence Data Mutation Protein Structure, Tertiary Protein Transport Proteome - metabolism Repetitive Sequences, Amino Acid RNA Interference
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