Superantigen Profile of Staphylococcus aureus Isolates from Patients with Steroid-Resistant Atopic Dermatitis

Background. Superantigens induce skin inflammatory responses in atopic dermatitis, which is commonly associated with Staphylococcus aureus infection. T cells activated in vitro by superantigens become steroid resistant. The objective was to assess the superantigen profiles of S. aureus isolates from...

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Veröffentlicht in:	Clinical infectious diseases 2008-05, Vol.46 (10), p.1562-1567
Hauptverfasser:	Schlievert, Patrick M., Case, Laura C., Strandberg, Kristi L., Abrams, Bea B., Leung, Donald Y. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases Antibodies, Bacterial - blood Antigens Articles and Commentaries Atopic dermatitis Bacterial diseases Bacterial Proteins - genetics Bacterial Proteins - immunology Bacterial Toxins - genetics Bacterial Toxins - immunology Biological and medical sciences Comparative analysis Dermatitis Dermatitis, Atopic - complications DNA, Bacterial - genetics Enterotoxins Enterotoxins - genetics Enterotoxins - immunology Female Human bacterial diseases Humans Immunopathology Infectious diseases Medical sciences Oxygen Polymerase Chain Reaction - methods Skin Skin allergic diseases. Stinging insect allergies Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcal Skin Infections - microbiology Staphylococcus Staphylococcus aureus Staphylococcus aureus - genetics Staphylococcus aureus - growth & development Staphylococcus aureus - isolation & purification Staphylococcus infections Steroids Superantigens Superantigens - genetics Superantigens - immunology T cell receptors T lymphocytes Toxicity Toxins Vagina - microbiology
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