The paradoxical effects of vitamin D on type 1 mediated immunity

Low vitamin D status is associated with an increased risk of Th1 mediated autoimmune diseases like inflammatory bowel disease. 1,25(OH) 2D 3 treatments have been shown to suppress Th1 mediated immunity and protect animals from experimental autoimmunity. Th1 mediated immunity is important for clearan...

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Veröffentlicht in:	Molecular aspects of medicine 2008-12, Vol.29 (6), p.369-375
Hauptverfasser:	Cantorna, Margherita T., Yu, Sanhong, Bruce, Danny
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmune Diseases - immunology Humans Immune regulation Infectious immunity Inflammatory bowel disease Inflammatory Bowel Diseases - immunology Kidney - enzymology Steroid Hydroxylases - metabolism Th1 Cells - immunology Th1 Cells - metabolism Vitamin D Vitamin D - metabolism
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