Fibrillin assembly requires fibronectin

Fibrillins constitute the major backbone of multifunctional microfibrils in elastic and nonelastic extracellular matrices. Proper assembly mechanisms are central to the formation and function of these microfibrils, and their properties are often compromised in pathological circumstances such as in M...

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Veröffentlicht in:	Molecular biology of the cell 2009-02, Vol.20 (3), p.846-858
Hauptverfasser:	Sabatier, Laetitia, Chen, Daliang, Fagotto-Kaufmann, Christine, Hubmacher, Dirk, McKee, Marc D, Annis, Douglas S, Mosher, Deane F, Reinhardt, Dieter P
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Binding Sites Child, Preschool Collagen - metabolism Dermis - cytology Extracellular Matrix - metabolism Fibrillin-1 Fibrillin-2 Fibrillins Fibroblasts - cytology Fibroblasts - metabolism Fibronectins - metabolism Fluorescent Dyes - metabolism Gelatin - metabolism Humans Male Microfilament Proteins - chemistry Microfilament Proteins - metabolism Molecular Sequence Data Molecular Weight Peptides - metabolism Protein Binding Protein Interaction Mapping Protein Structure, Quaternary Protein Transport Recombinant Proteins - metabolism
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