Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases

Abstract Recent studies highlight the prominent role played by estrogens in protecting the central nervous system (CNS) against the noxious consequences of a chronic inflammatory reaction. The neurodegenerative process of several CNS diseases, including Multiple Sclerosis, Alzheimer’s and Parkinson’...

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Veröffentlicht in:	Frontiers in neuroendocrinology 2008-10, Vol.29 (4), p.507-519
Hauptverfasser:	Vegeto, Elisabetta, Benedusi, Valeria, Maggi, Adriana
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - immunology Alzheimer Disease - pathology Alzheimer’s disease Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Brain - drug effects Endocrinology & Metabolism Estrogen Estrogens - pharmacology Estrogens - therapeutic use Humans Inflammation - drug therapy Menopause - drug effects Microglia Microglia - drug effects Microglia - metabolism Multiple sclerosis Multiple Sclerosis - immunology Multiple Sclerosis - pathology Neurodegenerative Diseases - drug therapy Neurodegenerative Diseases - immunology Neuroinflammation Parkinson Disease - immunology Parkinson Disease - pathology Parkinson’s disease
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