Case Report: Reconstruction of a 16-cm Diaphyseal Defect after Ewing’s Resection in a Child
Numerous options exist for intercalary segmental reconstruction after bone tumor resection. We present the extension of a recently developed surgical two-stage technique that involves insertion of a cement spacer, induction of a membrane, and reconstruction of the defect with cancellous and cortical...
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Veröffentlicht in: | Clinical orthopaedics and related research 2009-02, Vol.467 (2), p.572-577 |
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description | Numerous options exist for intercalary segmental reconstruction after bone tumor resection. We present the extension of a recently developed surgical two-stage technique that involves insertion of a cement spacer, induction of a membrane, and reconstruction of the defect with cancellous and cortical bone autograft in a 12-year-old child. The boy was referred to our center for treatment of a right femoral diaphyseal Ewing’s sarcoma. The first stage involved resection of the tumor and reconstruction with a locked intramedullary nail and a polymethylmethacrylate cement spacer. Seven months after the initial procedure during which adjuvant chemotherapy was given, the second-stage procedure was performed. The cement was removed and cancellous and cortical bone autograft was grafted in the membrane created around the cement spacer. Touchdown weightbearing was allowed immediately, partial weightbearing was resumed 6 weeks after the operation, and full weightbearing was allowed 4 months later. Successive plain radiographs showed rapid integration of the autograft to the host bone with bone union and cortical reconstitution. The principle of the induced membrane reconstruction seems applicable to intercalary segmental reconstruction after bone tumor resection in children. |
doi_str_mv | 10.1007/s11999-008-0605-9 |
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We present the extension of a recently developed surgical two-stage technique that involves insertion of a cement spacer, induction of a membrane, and reconstruction of the defect with cancellous and cortical bone autograft in a 12-year-old child. The boy was referred to our center for treatment of a right femoral diaphyseal Ewing’s sarcoma. The first stage involved resection of the tumor and reconstruction with a locked intramedullary nail and a polymethylmethacrylate cement spacer. Seven months after the initial procedure during which adjuvant chemotherapy was given, the second-stage procedure was performed. The cement was removed and cancellous and cortical bone autograft was grafted in the membrane created around the cement spacer. Touchdown weightbearing was allowed immediately, partial weightbearing was resumed 6 weeks after the operation, and full weightbearing was allowed 4 months later. Successive plain radiographs showed rapid integration of the autograft to the host bone with bone union and cortical reconstitution. 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We present the extension of a recently developed surgical two-stage technique that involves insertion of a cement spacer, induction of a membrane, and reconstruction of the defect with cancellous and cortical bone autograft in a 12-year-old child. The boy was referred to our center for treatment of a right femoral diaphyseal Ewing’s sarcoma. The first stage involved resection of the tumor and reconstruction with a locked intramedullary nail and a polymethylmethacrylate cement spacer. Seven months after the initial procedure during which adjuvant chemotherapy was given, the second-stage procedure was performed. The cement was removed and cancellous and cortical bone autograft was grafted in the membrane created around the cement spacer. Touchdown weightbearing was allowed immediately, partial weightbearing was resumed 6 weeks after the operation, and full weightbearing was allowed 4 months later. Successive plain radiographs showed rapid integration of the autograft to the host bone with bone union and cortical reconstitution. The principle of the induced membrane reconstruction seems applicable to intercalary segmental reconstruction after bone tumor resection in children.</description><subject>Biological and medical sciences</subject><subject>Bone Transplantation</subject><subject>Case Report</subject><subject>Chemotherapy, Adjuvant</subject><subject>Child</subject><subject>Conservative Orthopedics</subject><subject>Diseases of the osteoarticular system</subject><subject>Femoral Neoplasms - diagnosis</subject><subject>Femoral Neoplasms - drug therapy</subject><subject>Femoral Neoplasms - surgery</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Orthopedic Procedures - methods</subject><subject>Orthopedics</subject><subject>Reconstructive Surgical Procedures - methods</subject><subject>Sarcoma, Ewing - drug therapy</subject><subject>Sarcoma, Ewing - surgery</subject><subject>Sports Medicine</subject><subject>Surgery</subject><subject>Surgical Orthopedics</subject><subject>Transplantation, Autologous</subject><issn>0009-921X</issn><issn>1528-1132</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kdFqFTEQhoNY7Gn1AbyRRWjvoplkN7vxQiinVQsFQRS8kZBmJ-ek7EmOya7SO1_D1_NJzGEPrQpeDcN8_z8z_IQ8BfYCGGtfZgClFGWso0yyhqoHZAEN7yiA4A_JgjGmqOLw-ZAc5XxTWlE3_BE5BFUmgjcL8mVpMlYfcBvT-KpUG0Me02RHH0MVXWUqkNRuqnNvtuvbjGaoztGhHSvjRkzVxXcfVr9-_MxFm3GW-VBky7Uf-sfkwJkh45N9PSaf3lx8XL6jV-_fXi7PrqitVTvS2tZd35u66VxrZc8kd8rZtrGuVsiwd7Z8dy24KY0DkND3Co1xXErAHqU4Jq9n3-10vcHeYhiTGfQ2-Y1Jtzoar_-eBL_Wq_hNc8m7hnXF4HRvkOLXCfOoNz5bHAYTME5ZS9kJ4G1dwOf_gDdxSqE8p7kQsuMt7NxghmyKOSd0d5cA07vk9JycLsnpXXJaFc2zP1-4V-yjKsDJHjDZmsElE6zPdxwvjkKxHcdnLpdRWGG6v_D_238D-4eyfA</recordid><startdate>20090201</startdate><enddate>20090201</enddate><creator>Biau, David Jean</creator><creator>Pannier, Stéphanie</creator><creator>Masquelet, Alain Charles</creator><creator>Glorion, Christophe</creator><general>Springer-Verlag</general><general>Springer</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20090201</creationdate><title>Case Report: Reconstruction of a 16-cm Diaphyseal Defect after Ewing’s Resection in a Child</title><author>Biau, David Jean ; 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We present the extension of a recently developed surgical two-stage technique that involves insertion of a cement spacer, induction of a membrane, and reconstruction of the defect with cancellous and cortical bone autograft in a 12-year-old child. The boy was referred to our center for treatment of a right femoral diaphyseal Ewing’s sarcoma. The first stage involved resection of the tumor and reconstruction with a locked intramedullary nail and a polymethylmethacrylate cement spacer. Seven months after the initial procedure during which adjuvant chemotherapy was given, the second-stage procedure was performed. The cement was removed and cancellous and cortical bone autograft was grafted in the membrane created around the cement spacer. Touchdown weightbearing was allowed immediately, partial weightbearing was resumed 6 weeks after the operation, and full weightbearing was allowed 4 months later. 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subjects | Biological and medical sciences Bone Transplantation Case Report Chemotherapy, Adjuvant Child Conservative Orthopedics Diseases of the osteoarticular system Femoral Neoplasms - diagnosis Femoral Neoplasms - drug therapy Femoral Neoplasms - surgery Humans Magnetic Resonance Imaging Male Medical sciences Medicine Medicine & Public Health Orthopedic Procedures - methods Orthopedics Reconstructive Surgical Procedures - methods Sarcoma, Ewing - drug therapy Sarcoma, Ewing - surgery Sports Medicine Surgery Surgical Orthopedics Transplantation, Autologous |
title | Case Report: Reconstruction of a 16-cm Diaphyseal Defect after Ewing’s Resection in a Child |
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