Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially

Eosinophils are innate immune leukocytes implicated in the initiation and maintenance of type 2 immune responses, including asthma and allergy. The ability to store and rapidly secrete preformed cytokines distinguishes eosinophils from most lymphocytes, which must synthesize cytokine proteins prior...

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Veröffentlicht in:Journal of leukocyte biology 2009-01, Vol.85 (1), p.117-123
Hauptverfasser: Spencer, Lisa A., Szela, Craig T., Perez, Sandra A. C., Kirchhoffer, Casey L., Neves, Josiane S., Radke, Amy L., Weller, Peter F.
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Sprache:eng
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