The influence of gender on incidence and outcome of patients with bladder cancer in Harlem

Although African Americans have a lower incidence of bladder cancer, overall survival is worse compared with American whites. This phenomenon has been attributed to the higher incidence of advanced disease at diagnosis and poor follow-up. Fifty-nine cases of bladder cancer were identified through th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the National Medical Association 1999-03, Vol.91 (3), p.144-148
Hauptverfasser: HOKE, G. P, STONE, B. A, KLEIN, L, WILLIAMS, K. N
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 148
container_issue 3
container_start_page 144
container_title Journal of the National Medical Association
container_volume 91
creator HOKE, G. P
STONE, B. A
KLEIN, L
WILLIAMS, K. N
description Although African Americans have a lower incidence of bladder cancer, overall survival is worse compared with American whites. This phenomenon has been attributed to the higher incidence of advanced disease at diagnosis and poor follow-up. Fifty-nine cases of bladder cancer were identified through the Tumor Registry at Harlem Hospital and reviewed retrospectively. Complete data were obtained for 42 patients. The primary independent variables of interest were primary care utilization, comorbid conditions, social variables, and gender. The outcome variables of interest were stage of disease at presentation and death. The median age at diagnosis in this group was 73 years compared with 68 for bladder cancer patients in the United States. There was no statistically significant correlation between primary care utilization or severity of comorbidities, and clinical stage at presentation. Similarly, these variables did not influence the occurrence of death as an outcome. For women, the mean age at diagnosis was 74.2 years compared with 67.3 in men (P = .112). The ratio of male-to-female cases in this group was 1.3 to 1 compared with 2.7 to 1 for the general US population. Women had lower odds of being diagnosed with superficial disease (OR = 0.24, 95% CI, 0.06-0.94) and a higher incidence of a cancer-specific death (OR = 2.7, 95% CI). The poor outcome and high incidence of bladder cancer cases among women in Harlem is intriguing. Overall, primary care utilization, comorbidities, and other social factors did not seem to influence stage or death as an outcome. The significantly elevated prevalence of smoking among women in this community, increased age at diagnosis, and possible environmental influences may play a role.
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2608460</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>40526641</sourcerecordid><originalsourceid>FETCH-LOGICAL-p318t-26196a912bd3ff0a668112656249c65e46f2060f5171be0f3a0a9d9cf21de51f3</originalsourceid><addsrcrecordid>eNpdkEtLxDAUhYsozjj6FySIuCvcpG3abAQZ1BEG3OjGTUnzmMnQJjVpFf-9cRyfqwvnfudw7t1LppjlWZpTlu0nUwBSpoxW-SQ5CmEDABUrisNkgoFAxjCdJk8Pa4WM1e2orFDIabRSViqPnI2yMHIrcyuRGwfhui3S88EoOwT0aoY1alouPxyCR9RHF1pw36ruODnQvA3qZDdnyePN9cN8kS7vb-_mV8u0z3A1pIRiRjnDpJGZ1sAprTAmtKAkZ4IWKqeaAAVd4BI3CnTGgTPJhCZYqgLrbJZcfub2Y9MpKWIzz9u696bj_q123NR_N9as65V7qQmFKqcQAy52Ad49jyoMdWeCUG3LrXJjqCmjDGKhCJ79Azdu9DYeVxOcQwl5RSJ0-rvOd4-vn0fgfAfwIHirffybCT9cWTEAlr0DRnKLFg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>214070482</pqid></control><display><type>article</type><title>The influence of gender on incidence and outcome of patients with bladder cancer in Harlem</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>ProQuest Central UK/Ireland</source><source>PubMed Central</source><creator>HOKE, G. P ; STONE, B. A ; KLEIN, L ; WILLIAMS, K. N</creator><creatorcontrib>HOKE, G. P ; STONE, B. A ; KLEIN, L ; WILLIAMS, K. N</creatorcontrib><description>Although African Americans have a lower incidence of bladder cancer, overall survival is worse compared with American whites. This phenomenon has been attributed to the higher incidence of advanced disease at diagnosis and poor follow-up. Fifty-nine cases of bladder cancer were identified through the Tumor Registry at Harlem Hospital and reviewed retrospectively. Complete data were obtained for 42 patients. The primary independent variables of interest were primary care utilization, comorbid conditions, social variables, and gender. The outcome variables of interest were stage of disease at presentation and death. The median age at diagnosis in this group was 73 years compared with 68 for bladder cancer patients in the United States. There was no statistically significant correlation between primary care utilization or severity of comorbidities, and clinical stage at presentation. Similarly, these variables did not influence the occurrence of death as an outcome. For women, the mean age at diagnosis was 74.2 years compared with 67.3 in men (P = .112). The ratio of male-to-female cases in this group was 1.3 to 1 compared with 2.7 to 1 for the general US population. Women had lower odds of being diagnosed with superficial disease (OR = 0.24, 95% CI, 0.06-0.94) and a higher incidence of a cancer-specific death (OR = 2.7, 95% CI). The poor outcome and high incidence of bladder cancer cases among women in Harlem is intriguing. Overall, primary care utilization, comorbidities, and other social factors did not seem to influence stage or death as an outcome. The significantly elevated prevalence of smoking among women in this community, increased age at diagnosis, and possible environmental influences may play a role.</description><identifier>ISSN: 0027-9684</identifier><identifier>EISSN: 1943-4693</identifier><identifier>PMID: 10203916</identifier><identifier>CODEN: JNMAAE</identifier><language>eng</language><publisher>Thorofare, NJ: Slack</publisher><subject>Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Black or African American ; Black People ; Comorbidity ; Confidence Intervals ; Diabetes Mellitus - epidemiology ; Female ; Humans ; Incidence ; Male ; Medical sciences ; Middle Aged ; Neoplasm Staging ; Nephrology. Urinary tract diseases ; New York - epidemiology ; Odds Ratio ; Registries ; Retrospective Studies ; Risk Factors ; Sex Distribution ; Survival Rate ; Treatment Outcome ; Tumors of the urinary system ; Urinary Bladder Neoplasms - epidemiology ; Urinary Bladder Neoplasms - pathology ; Urinary Bladder Neoplasms - therapy ; Urinary tract. Prostate gland ; White People</subject><ispartof>Journal of the National Medical Association, 1999-03, Vol.91 (3), p.144-148</ispartof><rights>1999 INIST-CNRS</rights><rights>Copyright Slack, Incorporated Mar 1999</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2608460/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/214070482?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53791,53793,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=1789009$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10203916$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HOKE, G. P</creatorcontrib><creatorcontrib>STONE, B. A</creatorcontrib><creatorcontrib>KLEIN, L</creatorcontrib><creatorcontrib>WILLIAMS, K. N</creatorcontrib><title>The influence of gender on incidence and outcome of patients with bladder cancer in Harlem</title><title>Journal of the National Medical Association</title><addtitle>J Natl Med Assoc</addtitle><description>Although African Americans have a lower incidence of bladder cancer, overall survival is worse compared with American whites. This phenomenon has been attributed to the higher incidence of advanced disease at diagnosis and poor follow-up. Fifty-nine cases of bladder cancer were identified through the Tumor Registry at Harlem Hospital and reviewed retrospectively. Complete data were obtained for 42 patients. The primary independent variables of interest were primary care utilization, comorbid conditions, social variables, and gender. The outcome variables of interest were stage of disease at presentation and death. The median age at diagnosis in this group was 73 years compared with 68 for bladder cancer patients in the United States. There was no statistically significant correlation between primary care utilization or severity of comorbidities, and clinical stage at presentation. Similarly, these variables did not influence the occurrence of death as an outcome. For women, the mean age at diagnosis was 74.2 years compared with 67.3 in men (P = .112). The ratio of male-to-female cases in this group was 1.3 to 1 compared with 2.7 to 1 for the general US population. Women had lower odds of being diagnosed with superficial disease (OR = 0.24, 95% CI, 0.06-0.94) and a higher incidence of a cancer-specific death (OR = 2.7, 95% CI). The poor outcome and high incidence of bladder cancer cases among women in Harlem is intriguing. Overall, primary care utilization, comorbidities, and other social factors did not seem to influence stage or death as an outcome. The significantly elevated prevalence of smoking among women in this community, increased age at diagnosis, and possible environmental influences may play a role.</description><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Black or African American</subject><subject>Black People</subject><subject>Comorbidity</subject><subject>Confidence Intervals</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Nephrology. Urinary tract diseases</subject><subject>New York - epidemiology</subject><subject>Odds Ratio</subject><subject>Registries</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sex Distribution</subject><subject>Survival Rate</subject><subject>Treatment Outcome</subject><subject>Tumors of the urinary system</subject><subject>Urinary Bladder Neoplasms - epidemiology</subject><subject>Urinary Bladder Neoplasms - pathology</subject><subject>Urinary Bladder Neoplasms - therapy</subject><subject>Urinary tract. Prostate gland</subject><subject>White People</subject><issn>0027-9684</issn><issn>1943-4693</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpdkEtLxDAUhYsozjj6FySIuCvcpG3abAQZ1BEG3OjGTUnzmMnQJjVpFf-9cRyfqwvnfudw7t1LppjlWZpTlu0nUwBSpoxW-SQ5CmEDABUrisNkgoFAxjCdJk8Pa4WM1e2orFDIabRSViqPnI2yMHIrcyuRGwfhui3S88EoOwT0aoY1alouPxyCR9RHF1pw36ruODnQvA3qZDdnyePN9cN8kS7vb-_mV8u0z3A1pIRiRjnDpJGZ1sAprTAmtKAkZ4IWKqeaAAVd4BI3CnTGgTPJhCZYqgLrbJZcfub2Y9MpKWIzz9u696bj_q123NR_N9as65V7qQmFKqcQAy52Ad49jyoMdWeCUG3LrXJjqCmjDGKhCJ79Azdu9DYeVxOcQwl5RSJ0-rvOd4-vn0fgfAfwIHirffybCT9cWTEAlr0DRnKLFg</recordid><startdate>19990301</startdate><enddate>19990301</enddate><creator>HOKE, G. P</creator><creator>STONE, B. A</creator><creator>KLEIN, L</creator><creator>WILLIAMS, K. N</creator><general>Slack</general><general>Elsevier Limited</general><general>National Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>4T-</scope><scope>4U-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19990301</creationdate><title>The influence of gender on incidence and outcome of patients with bladder cancer in Harlem</title><author>HOKE, G. P ; STONE, B. A ; KLEIN, L ; WILLIAMS, K. N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p318t-26196a912bd3ff0a668112656249c65e46f2060f5171be0f3a0a9d9cf21de51f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Black or African American</topic><topic>Black People</topic><topic>Comorbidity</topic><topic>Confidence Intervals</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Nephrology. Urinary tract diseases</topic><topic>New York - epidemiology</topic><topic>Odds Ratio</topic><topic>Registries</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sex Distribution</topic><topic>Survival Rate</topic><topic>Treatment Outcome</topic><topic>Tumors of the urinary system</topic><topic>Urinary Bladder Neoplasms - epidemiology</topic><topic>Urinary Bladder Neoplasms - pathology</topic><topic>Urinary Bladder Neoplasms - therapy</topic><topic>Urinary tract. Prostate gland</topic><topic>White People</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HOKE, G. P</creatorcontrib><creatorcontrib>STONE, B. A</creatorcontrib><creatorcontrib>KLEIN, L</creatorcontrib><creatorcontrib>WILLIAMS, K. N</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Science Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the National Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HOKE, G. P</au><au>STONE, B. A</au><au>KLEIN, L</au><au>WILLIAMS, K. N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The influence of gender on incidence and outcome of patients with bladder cancer in Harlem</atitle><jtitle>Journal of the National Medical Association</jtitle><addtitle>J Natl Med Assoc</addtitle><date>1999-03-01</date><risdate>1999</risdate><volume>91</volume><issue>3</issue><spage>144</spage><epage>148</epage><pages>144-148</pages><issn>0027-9684</issn><eissn>1943-4693</eissn><coden>JNMAAE</coden><abstract>Although African Americans have a lower incidence of bladder cancer, overall survival is worse compared with American whites. This phenomenon has been attributed to the higher incidence of advanced disease at diagnosis and poor follow-up. Fifty-nine cases of bladder cancer were identified through the Tumor Registry at Harlem Hospital and reviewed retrospectively. Complete data were obtained for 42 patients. The primary independent variables of interest were primary care utilization, comorbid conditions, social variables, and gender. The outcome variables of interest were stage of disease at presentation and death. The median age at diagnosis in this group was 73 years compared with 68 for bladder cancer patients in the United States. There was no statistically significant correlation between primary care utilization or severity of comorbidities, and clinical stage at presentation. Similarly, these variables did not influence the occurrence of death as an outcome. For women, the mean age at diagnosis was 74.2 years compared with 67.3 in men (P = .112). The ratio of male-to-female cases in this group was 1.3 to 1 compared with 2.7 to 1 for the general US population. Women had lower odds of being diagnosed with superficial disease (OR = 0.24, 95% CI, 0.06-0.94) and a higher incidence of a cancer-specific death (OR = 2.7, 95% CI). The poor outcome and high incidence of bladder cancer cases among women in Harlem is intriguing. Overall, primary care utilization, comorbidities, and other social factors did not seem to influence stage or death as an outcome. The significantly elevated prevalence of smoking among women in this community, increased age at diagnosis, and possible environmental influences may play a role.</abstract><cop>Thorofare, NJ</cop><pub>Slack</pub><pmid>10203916</pmid><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0027-9684
ispartof Journal of the National Medical Association, 1999-03, Vol.91 (3), p.144-148
issn 0027-9684
1943-4693
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2608460
source MEDLINE; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; PubMed Central
subjects Adult
Age Distribution
Aged
Aged, 80 and over
Biological and medical sciences
Black or African American
Black People
Comorbidity
Confidence Intervals
Diabetes Mellitus - epidemiology
Female
Humans
Incidence
Male
Medical sciences
Middle Aged
Neoplasm Staging
Nephrology. Urinary tract diseases
New York - epidemiology
Odds Ratio
Registries
Retrospective Studies
Risk Factors
Sex Distribution
Survival Rate
Treatment Outcome
Tumors of the urinary system
Urinary Bladder Neoplasms - epidemiology
Urinary Bladder Neoplasms - pathology
Urinary Bladder Neoplasms - therapy
Urinary tract. Prostate gland
White People
title The influence of gender on incidence and outcome of patients with bladder cancer in Harlem
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T00%3A06%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20influence%20of%20gender%20on%20incidence%20and%20outcome%20of%20patients%20with%20bladder%20cancer%20in%20Harlem&rft.jtitle=Journal%20of%20the%20National%20Medical%20Association&rft.au=HOKE,%20G.%20P&rft.date=1999-03-01&rft.volume=91&rft.issue=3&rft.spage=144&rft.epage=148&rft.pages=144-148&rft.issn=0027-9684&rft.eissn=1943-4693&rft.coden=JNMAAE&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E40526641%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=214070482&rft_id=info:pmid/10203916&rfr_iscdi=true