Plasma coenzyme Q10 predicts lipid-lowering response to high-dose atorvastatin

Background Coenzyme Q10 (CoQ10) is a provitamin synthesized via the 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase pathway, and thus may serve as a potential marker of intrinsic HMG-CoA reductase activity. HMG-CoA reductase inhibitors (statins) decrease CoQ10, although it is unclear whet...

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Veröffentlicht in:	Journal of clinical lipidology 2008-08, Vol.2 (4), p.289-297
Hauptverfasser:	Pacanowski, Michael A., PharmD, MPH, Frye, Reginald F., PharmD, PhD, Enogieru, Osatohanmen, Schofield, Richard S., MD, Zineh, Issam, PharmD
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Cardiovascular Coenzyme Q10 HMG CoA-reductase inhibitors Lipids Pharmacology
Online-Zugang:	Volltext
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