Nanoparticle pharmacokinetic profiling in vivo using magnetic resonance imaging

Contrast agents targeted to molecular markers of disease are currently being developed with the goal of identifying disease early and evaluating treatment effectiveness using noninvasive imaging modalities such as MRI. Pharmacokinetic profiling of the binding of targeted contrast agents, while theor...

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Veröffentlicht in:	Magnetic resonance in medicine 2008-12, Vol.60 (6), p.1353-1361
Hauptverfasser:	Neubauer, Anne M., Sim, Hoon, Winter, Patrick M., Caruthers, Shelton D., Williams, Todd A., Robertson, J. David, Sept, David, Lanza, Gregory M., Wickline, Samuel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis - metabolism Atherosclerosis - pathology binding Contrast Media - pharmacokinetics Gadolinium - pharmacokinetics Gene Expression Profiling - methods Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Integrin alphaVbeta3 - metabolism Magnetic Resonance Imaging - methods Molecular Probe Techniques Nanoparticles pharmacokinetic Rabbits αvβ3-integrin
Online-Zugang:	Volltext
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