Magnetic resonance detection of kidney iron deposition in sickle cell disease: A marker of chronic hemolysis

Purpose To study the pattern, etiology, and significance of renal iron accumulation in chronically transfused sickle cell disease (SCD) and thalassemia major (TM) patients using magnetic resonance imaging (MRI). Materials and Methods Magnetic resonance imaging (MRI) was performed in 75 SCD patients,...

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Veröffentlicht in:	Journal of magnetic resonance imaging 2008-09, Vol.28 (3), p.698-704
Hauptverfasser:	Schein, Aaron, Enriquez, Cathleen, Coates, Thomas D., Wood, John C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Algorithms Anemia, Hemolytic - diagnosis Anemia, Hemolytic - metabolism Anemia, Sickle Cell - diagnosis Anemia, Sickle Cell - metabolism Biomarkers - analysis Chronic Disease Female hemolysis Humans Image Interpretation, Computer-Assisted - methods iron Iron - analysis Iron Overload - diagnosis Iron Overload - metabolism kidney Kidney - chemistry Magnetic Resonance Imaging - methods Male relaxometry Reproducibility of Results Sensitivity and Specificity sickle cell disease thalassemia Young Adult
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