The Proto-oncogene SET Interacts with Muscarinic Receptors and Attenuates Receptor Signaling

G protein-coupled receptors mediate cell responses to extracellular stimuli and likely function in the context of a larger signal transduction complex. Utilizing the third intracellular loop of a G protein-coupled receptor in glutathione S-transferase pulldown assays from rat brain lysates coupled w...

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Veröffentlicht in:	The Journal of biological chemistry 2006-12, Vol.281 (52), p.40310-40320
Hauptverfasser:	Simon, Violaine, Guidry, Jessie, Gettys, Thomas W., Tobin, Andrew B., Lanier, Stephen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals CHO Cells Chromosomal Proteins, Non-Histone - deficiency Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism Chromosomal Proteins, Non-Histone - physiology Cricetinae DNA-Binding Proteins Histone Chaperones Humans Intracellular Fluid - metabolism Intracellular Fluid - physiology Mice Molecular Sequence Data Protein Binding - genetics Protein Binding - physiology Protein Structure, Tertiary - genetics Proto-Oncogene Proteins - deficiency Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins - physiology Rats Receptor, Muscarinic M2 - biosynthesis Receptor, Muscarinic M2 - genetics Receptor, Muscarinic M2 - metabolism Receptor, Muscarinic M2 - physiology Receptor, Muscarinic M3 - antagonists & inhibitors Receptor, Muscarinic M3 - genetics Receptor, Muscarinic M3 - metabolism Receptor, Muscarinic M3 - physiology Receptors, G-Protein-Coupled - metabolism Receptors, G-Protein-Coupled - physiology RNA, Small Interfering - genetics Signal Transduction - genetics Signal Transduction - physiology Transcription Factors - deficiency Transcription Factors - genetics Transcription Factors - metabolism Transcription Factors - physiology
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