The Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke : The CLEAR Stroke Trial

Multiple approaches are being studied to enhance the rate of thrombolysis for acute ischemic stroke. Treatment of myocardial infarction with a combination of a reduced-dose fibrinolytic agent and a glycoprotein (GP) IIb/IIIa receptor antagonist has been shown to improve the rate of recanalization ve...

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Veröffentlicht in:	Stroke (1970) 2008-12, Vol.39 (12), p.3268-3276
Hauptverfasser:	PANCIOLI, Arthur M, BRODERICK, Joseph, CASTALDO, John, FREY, James, GEBEL, James, KASNER, Scott, KIDWELL, Chelsea, KWIATKOWSKI, Thomas, LIBMAN, Richard, MACKENZIE, Richard, SCOTT, Phillip, STARKMAN, Sidney, BROTT, Thomas, THURMAN, R. Jason, TOMSICK, Thomas, KHOURY, Jane, BEAN, Judy, DEL ZOPPO, Gregory, KLEINDORFER, Dawn, WOO, Daniel, KHATRI, Pooja
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Aged Aged, 80 and over Biological and medical sciences Brain Ischemia - drug therapy Cerebral Hemorrhage - chemically induced Cerebral Hemorrhage - epidemiology Combined Modality Therapy Dose-Response Relationship, Drug Double-Blind Method Drug Therapy, Combination Female Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - adverse effects Fibrinolytic Agents - therapeutic use Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hemorrhage - chemically induced Hemorrhage - epidemiology Humans Male Medical sciences Middle Aged Nervous system (semeiology, syndromes) Neurology Peptides - administration & dosage Peptides - adverse effects Peptides - therapeutic use Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - adverse effects Platelet Aggregation Inhibitors - therapeutic use Recombinant Proteins - administration & dosage Recombinant Proteins - adverse effects Recombinant Proteins - therapeutic use Severity of Illness Index Thrombolytic Therapy Tissue Plasminogen Activator - administration & dosage Tissue Plasminogen Activator - adverse effects Tissue Plasminogen Activator - therapeutic use Vascular diseases and vascular malformations of the nervous system
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