The Tyrosine Phosphatase STEP Mediates AMPA Receptor Endocytosis after Metabotropic Glutamate Receptor Stimulation

Although it is well established that AMPA receptor (AMPAR) trafficking is a central event in several forms of synaptic plasticity, the mechanisms that regulate the surface expression of AMPARs are poorly understood. Previous work has shown that striatal-enriched protein tyrosine phosphatase (STEP) m...

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Veröffentlicht in:	The Journal of neuroscience 2008-10, Vol.28 (42), p.10561-10566
Hauptverfasser:	Zhang, Yang, Venkitaramani, Deepa V, Gladding, Clare M, Zhang, Yongfang, Kurup, Pradeep, Molnar, Elek, Collingridge, Graham L, Lombroso, Paul J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brief Communications Cells, Cultured Endocytosis - drug effects Endocytosis - physiology Hippocampus - drug effects Hippocampus - enzymology Hippocampus - metabolism Male Methoxyhydroxyphenylglycol - analogs & derivatives Methoxyhydroxyphenylglycol - pharmacology Mice Mice, Knockout Neurons - drug effects Neurons - enzymology Neurons - metabolism Protein Tyrosine Phosphatases, Non-Receptor - physiology Rats Rats, Sprague-Dawley Receptors, AMPA - metabolism Receptors, Metabotropic Glutamate - agonists Receptors, Metabotropic Glutamate - metabolism
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