Virus Capsid Expansion Driven by the Capture of Mobile Surface Loops

The capsids of tailed-DNA bacteriophages first assemble as procapsids, which mature by converting into a new form that is strong enough to contain a densely packed viral chromosome. We demonstrate that the intersubunit crosslinking that occurs during maturation of HK97 capsids actually promotes the...

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Veröffentlicht in:	Structure (London) 2008-10, Vol.16 (10), p.1491-1502
Hauptverfasser:	Lee, Kelly K., Gan, Lu, Tsuruta, Hiro, Moyer, Crystal, Conway, James F., Duda, Robert L., Hendrix, Roger W., Steven, Alasdair C., Johnson, John E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Capsid Proteins - chemistry Capsid Proteins - metabolism MICROBIO Models, Biological Models, Molecular Movement Multiprotein Complexes - chemistry Multiprotein Complexes - metabolism Protein Binding Protein Structure, Quaternary Protein Structure, Secondary PROTEINS Virion - chemistry Virion - metabolism Virus Assembly - physiology
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