A3 Adenosine Receptor Signaling Influences Pulmonary Inflammation and Fibrosis

Adenosine is a signaling molecule produced during conditions that cause cellular stress or damage. This signaling pathway is implicated in the regulation of pulmonary disorders through the selective engagement of adenosine receptors. The goal of this study was to examine the involvement of the A(3)...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2008-12, Vol.39 (6), p.697-705
Hauptverfasser:	Morschl, Eva, Molina, Jose G, Volmer, Jonathan B, Mohsenin, Amir, Pero, Ralph S, Hong, Jeong-Soo, Kheradmand, Farrah, Lee, James J, Blackburn, Michael R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bleomycin Cell Movement Eosinophils - pathology Female Gene Expression Regulation Lung - enzymology Lung - pathology Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Mice Pneumonia - complications Pneumonia - metabolism Protein Transport Pulmonary Fibrosis - complications Pulmonary Fibrosis - metabolism Receptor, Adenosine A3 - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Signal Transduction Tissue Inhibitor of Metalloproteinase-1 - metabolism Transforming Growth Factor beta1 - genetics Transforming Growth Factor beta1 - metabolism
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