Targeting of mitochondria by 10-N-alkyl acridine orange analogues: role of alkyl chain length in determining cellular uptake and localization

10-N-Nonyl acridine orange (NAO) is used as a mitochondrial probe because of its high affinity for cardiolipin (CL). Targeting of NAO may also depend on mitochondrial membrane potential. As the nonyl group has been considered essential for targeting, a systematic study of alkyl chain length was unde...

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Veröffentlicht in:Mitochondrion 2008-06, Vol.8 (3), p.237-246
Hauptverfasser: Rodriguez, Myriam E, Azizuddin, Kashif, Zhang, Ping, Chiu, Song-mao, Lam, Minh, Kenney, Malcolm E, Burda, Clemens, Oleinick, Nancy L
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Sprache:eng
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