Gender-Specific Expression and Mechanism of Regulation of Estrogen Sulfotransferase in Adipose Tissues of the Mouse

Although primarily regarded as a sex steroid, estrogen plays an important role in many other physiological processes including adipose development and disposition. Estrogen sulfotransferase (EST) regulates estrogen activity by catalyzing the sulfoconjugation and inactivation of estrogens. In the pre...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2008-11, Vol.149 (11), p.5440-5448
Hauptverfasser:	Khor, Victor K, Tong, Ming Han, Qian, Yueming, Song, Wen-Chao
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Adipocytes Adipose tissue Adipose Tissue - drug effects Adipose Tissue - enzymology Adipose Tissue - metabolism Adiposity - genetics Animal tissues Animals Bioaccumulation Biological and medical sciences Body fat Castration Estrogens Female Females Fractionation Fundamental and applied biological sciences. Psychology Gender Gene Expression Regulation, Enzymologic - drug effects Inactivation Liver Liver - drug effects Liver - metabolism Liver X receptors Male Mice Mice, Inbred C57BL Mice, Knockout Organ Specificity - drug effects Organ Specificity - genetics Physiological effects Physiology Sex Characteristics Sex differences Sexual dimorphism Sulfotransferase Sulfotransferases - genetics Sulfotransferases - metabolism Testosterone Testosterone - pharmacology Vertebrates: endocrinology
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